Description

Alcian Blue 8Gx is a synthetic, cationic phthalocyanine dye widely recognized for its strong affinity to acidic polysaccharides. This property makes it an indispensable tool in histology and cytology for the selective staining of mucins, glycoproteins, and other anionic tissue components. It is a critical reagent for researchers and diagnostic laboratories in life sciences, pathology, and biomedical research, providing clear visualization of cellular structures. The compound is supplied under the identifier CAS NO 33864-99-2.

Application

• Histological Staining: Primary application for staining acidic mucopolysaccharides (e.g., in cartilage, goblet cells, connective tissue) in biological tissue sections.
• Cytological Analysis: Used in cytology smears to identify and differentiate cells containing acidic glycoconjugates.
• Biomedical Research: A key tool in glycobiology and histochemistry studies to investigate carbohydrate distribution and composition in cells and tissues.
• Pathology and Diagnostics: Employed in diagnostic laboratories to aid in the identification of certain tumors and diseases characterized by abnormal mucin production.
• Combined Staining Protocols: Often used in sequence with other stains like Periodic acid–Schiff (PAS) for comprehensive tissue analysis (Alcian Blue-PAS staining).
• Material Science: Potential use as a colorant or a functional dye in specialized material applications due to its phthalocyanine structure.

Basic Information

Product Name	Alcian Blue 8Gx
CAS No.	33864-99-2
Molecular Formula	C56H68Cl4CuN16S4
Molecular Weight	1298.86 g/mol
Synonyms	Alcian Blue 8G; Ingrain Blue 1; C.I. 74240; C.I. Pigment Blue 80; Copper phthalocyanine tetramethyl derivative; Tetrakis(methylpyridinium) chloride copper phthalocyanine; Astra Blue; Alcian Blue 8GN
EINECS	251-689-3

Quality Control

Our Alcian Blue 8Gx is manufactured under strict quality management systems to ensure batch-to-batch consistency and performance in sensitive staining applications. Each lot is tested for critical parameters including identity, purity, and staining performance. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability and performance.

Specification

Item	Specification
Appearance	Dark blue to greenish-blue powder
Identification (IR)	Conforms to structure
Assay (Dye Content)	≥ 95.0%
Loss on Drying	≤ 5.0%
Solubility	Soluble in water, slightly soluble in ethanol
Staining Performance	Meets biological staining standards

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.