Description

3-Phenyl-n-(Trifluoroacetyl)-n-Acetyl-L-Alanine Methyl Ester is a specialized, high-purity chiral building block and protected amino acid derivative. This compound is critical for researchers and manufacturers requiring precise stereochemistry and functional group manipulation in complex organic syntheses. It is primarily utilized in the development of novel pharmaceuticals, particularly in peptide mimetics and active pharmaceutical ingredient (API) research, where its trifluoroacetyl and acetyl protecting groups offer strategic advantages.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce modified alanine residues with specific protecting group strategies.
• Proteomics Research: Serves as a reagent or standard in biochemical studies involving amino acid analysis and protein sequencing methodologies.
• Chemical Biology: Employed in the synthesis of activity-based probes and other tools for studying biological pathways and mechanisms.
• Agrochemical Development: Potential intermediate in the synthesis of advanced, chiral crop protection agents with enhanced efficacy.
• Academic & Industrial R&D: A valuable compound for methodological development in asymmetric synthesis and organofluorine chemistry.

Basic Information

Product Name	3-Phenyl-n-(Trifluoroacetyl)-n-Acetyl-L-Alanine Methyl Ester
CAS No.	33858-09-2
Molecular Formula	C₁₄H₁₄F₃NO₄
Molecular Weight	317.26 g/mol
Synonyms	L-Alanine, N-[2-(trifluoroacetyl)-1-oxo-2-phenylethyl]-, methyl ester; Methyl N-(trifluoroacetyl)-N-acetyl-3-phenyl-L-alaninate; N-(Trifluoroacetyl)-N-acetyl-3-phenyl-L-alanine methyl ester; N-[(S)-1-Methoxycarbonyl-2-phenylethyl]-2,2,2-trifluoroacetamide; N-Acetyl-N-trifluoroacetyl-3-phenyl-L-alanine methyl ester; Protected L-Phenylalanine derivative; Chiral Alanine Ester Building Block
EINECS	Contact for details

Quality Control

Our 3-Phenyl-n-(Trifluoroacetyl)-n-Acetyl-L-Alanine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (L-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.