Description

1-O,2-O,3-O,5-O,6-o-Pentakis(Trimethylsilyl)-L-Chiro-Inositol [Phosphoric Acid Bis(Trimethylsilyl)] Ester is a highly functionalized, silyl-protected derivative of L-chiro-inositol phosphate, designed for advanced synthetic and biochemical applications. This compound is a critical protected intermediate that enables precise chemical transformations while safeguarding sensitive functional groups. It is primarily utilized by pharmaceutical researchers and specialty chemical manufacturers involved in the synthesis of complex bioactive molecules, including inositol phosphates and their analogs.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the production of novel drug candidates, particularly those targeting metabolic and neurological pathways.
• Research & Development of Inositol Derivatives: Used in academic and industrial R&D to explore the structure-activity relationships of phosphorylated inositols and their biological functions.
• Synthesis of Protected Nucleosides and Nucleotides: Acts as a sophisticated reagent for introducing protected phosphate-inositol motifs into larger molecular architectures.
• Biochemical Probe Development: Facilitates the creation of labeled or modified inositol phosphate probes for studying cellular signaling pathways, such as the phosphoinositide cycle.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for high-value fine chemicals and Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	1-O,2-O,3-O,5-O,6-o-Pentakis(Trimethylsilyl)-L-Chiro-Inositol [Phosphoric Acid Bis(Trimethylsilyl)] Ester
CAS No.	33800-40-7
Molecular Formula	C27H67O9PSi7
Molecular Weight	779.43 g/mol
Synonyms	L-Chiro-Inositol, 1,2,3,5,6-pentakis-O-(trimethylsilyl)-, cyclic bis(trimethylsilyl) phosphate; Pentakis(trimethylsilyl)-L-chiro-inositol cyclic bis(trimethylsilyl) phosphate; 1,2,3,5,6-Pentakis-O-(trimethylsilyl)-myo-inositol 4-cyclic bis(trimethylsilyl) phosphate (L-chiro form); Protected L-chiro-inositol phosphate; TMS-L-chiro-inositol phosphate ester; Cyclic bis(trimethylsilyl) phosphoric acid ester of pentakis-O-TMS-L-chiro-inositol
EINECS	Contact for details

Quality Control

Every batch of our 1-O,2-O,3-O,5-O,6-o-Pentakis(Trimethylsilyl)-L-Chiro-Inositol [Phosphoric Acid Bis(Trimethylsilyl)] Ester is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including NMR, HPLC, and GC to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets the rigorous standards required for research and process chemistry applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. For long-term storage, consider storing under an inert gas blanket in a desiccator.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 90.0% (Total TMS derivatives)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.