Description

1-O,2-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-L-Myo-Inositol 3-[Phosphoric Acid Bis(Trimethylsilyl)] Ester is a highly functionalized, fully protected derivative of myo-inositol, a key biological signaling molecule. This compound is specifically engineered as a critical synthetic intermediate, offering exceptional versatility for advanced organic and medicinal chemistry research. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel inositol phosphate analogs, enzyme inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex inositol phosphate derivatives and phosphatidylinositol (PI) analogs for drug discovery programs.
• Medicinal Chemistry Research: Used to investigate cell signaling pathways, particularly those involving phosphoinositides, for potential therapeutic targets.
• Biochemical Probe Development: Serves as a precursor for labeled (e.g., fluorescent, isotopic) inositol compounds used in biological assays and diagnostic research.
• Glycobiology Studies: Employed in the synthesis of complex carbohydrate and glycoconjugate molecules due to its protected, reactive hydroxyl groups.
• Chemical Biology Tool: Facilitates the study of enzymes like kinases and phosphatases that act on inositol substrates.
• Fine Chemical Synthesis: Acts as a versatile chiral starting material for the production of high-value, specialized chemicals in contract manufacturing.

Basic Information

Product Name	1-O,2-O,4-O,5-O,6-o-Pentakis(Trimethylsilyl)-L-Myo-Inositol 3-[Phosphoric Acid Bis(Trimethylsilyl)] Ester
CAS No.	33800-38-3
Molecular Formula	C27H69O9PSi7
Molecular Weight	777.43 g/mol
Synonyms	L-myo-Inositol, 1,2,4,5,6-pentakis-O-(trimethylsilyl)-, 3-(bis(trimethylsilyl) phosphate); 1,2,4,5,6-Penta-O-trimethylsilyl-myo-inositol 3-(bis(trimethylsilyl) phosphate); myo-Inositol, 1,2,4,5,6-pentakis-O-(trimethylsilyl)-, 3-(bis(trimethylsilyl) phosphate), L-; Fully Protected myo-Inositol Phosphate TMS Ester; Hexakis(trimethylsilyl) myo-Inositol Phosphate Derivative; Inositol Phosphate, Heptakis(trimethylsilyl) Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced synthetic intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including NMR (¹H, ¹³C, ³¹P), HPLC, and mass spectrometry to confirm identity and purity. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and degradation. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.