Description

(S)-2-(Toluene-4-Sulfonyloxy)-Propionic Acid Ethyl Ester is a high-purity chiral building block and key intermediate in advanced organic synthesis. This compound is valued for its role in introducing the (S)-configured propionate moiety, enabling the stereoselective construction of complex molecules. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), antiviral agents, and other optically active APIs.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing molecular libraries.
• Material Science: Potential intermediate for creating chiral polymers or liquid crystals with specific optical properties.

Basic Information

Product Name	(S)-2-(Toluene-4-Sulfonyloxy)-Propionic Acid Ethyl Ester
CAS No.	33798-77-5
Molecular Formula	C₁₂H₁₆O₅S
Molecular Weight	272.32 g/mol
Synonyms	(S)-Ethyl 2-((4-methylphenyl)sulfonyloxy)propanoate; (S)-Ethyl 2-(p-toluenesulfonyloxy)propionate; (S)-Ethyl 2-(tosyloxy)propionate; (S)-Tosyloxypropionic Acid Ethyl Ester; (S)-2-(p-Toluenesulfonyloxy)propionic Acid Ethyl Ester; (S)-2-(4-Methylbenzenesulfonyloxy)propionic Acid Ethyl Ester; (S)-Ethyl 2-[(4-methylphenyl)sulfonyl]oxypropanoate; (S)-ETP
EINECS	Contact for details

Quality Control

Our (S)-2-(Toluene-4-Sulfonyloxy)-Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.