Description

(-)-Mono-(1R)-Menthyl Phthalate CAS NO 33744-74-0 is a high-purity chiral derivative of phthalic acid, specifically esterified with (1R)-menthol. This compound is valued as a key chiral auxiliary and resolving agent in asymmetric synthesis and stereochemistry research. It is essential for industries requiring precise enantiomeric control, including pharmaceutical intermediates, advanced material science, and specialty chemical manufacturing.

Application

• As a chiral resolving agent for the separation of racemic mixtures of acids and amines.
• As a chiral auxiliary in asymmetric synthesis to induce stereoselectivity.
• In the research and development of pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• For the synthesis of liquid crystal materials and other advanced organic compounds.
• As a standard or reference material in analytical chemistry and quality control laboratories.
• In academic and industrial stereochemistry studies and method development.

Basic Information

Product Name	(-)-Mono-(1R)-Menthyl Phthalate
CAS No.	33744-74-0
Molecular Formula	C₁₉H₂₄O₄
Molecular Weight	316.39 g/mol
Synonyms	(-)-Menthyl Hydrogen Phthalate; (1R)-(-)-Menthyl Hydrogen Phthalate; L-Menthyl Hydrogen Phthalate; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Hydrogen Phthalate; Mono-(-)-menthyl Phthalate; Phthalic Acid Mono-(-)-menthyl Ester; (-)-MPA; Chiral Menthyl Phthalate
EINECS	Contact for details

Quality Control

Our (-)-Mono-(1R)-Menthyl Phthalate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) documenting identity, purity, and specific rotation are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation [α]²⁰D	-50° to -55° (c=1 in CHCl₃)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.