Description

Hypophyllanthin CAS NO 33676-00-5 is a naturally occurring lignan compound, a secondary metabolite found in certain Phyllanthus species. This phytochemical is of significant interest for its potential bioactive properties, making it a valuable reference standard and research material. It is primarily utilized by the pharmaceutical, nutraceutical, and academic research sectors for applications in drug discovery, phytochemical analysis, and the development of standardized herbal extracts.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for the quality control and standardization of herbal medicines and botanical extracts.
• Bioactivity Research: Serves as a key compound in pharmacological studies investigating antioxidant, hepatoprotective, and anti-inflammatory activities.
• Natural Product Chemistry: Essential for isolation, identification, and structural elucidation workflows in academic and industrial R&D laboratories.
• Nutraceutical Development: Employed in the formulation and standardization of dietary supplements to ensure consistent potency and efficacy.
• Analytical Method Development: Used as a calibration standard in chromatographic methods (HPLC, LC-MS) for quantitative analysis of complex plant matrices.

Basic Information

Product Name	Hypophyllanthin
CAS No.	33676-00-5
Molecular Formula	C24H30O7
Molecular Weight	430.49 g/mol
Synonyms	Hypophyllanthin; (-)-Hypophyllanthin; Phyllanthin isomer; 4-[(3,4-Dimethoxyphenyl)methyl]-2,6-dimethoxyphenyl 3,4,5-trimethoxybenzoate; Lignan from Phyllanthus amarus; Nirphyllin
EINECS	Contact for details

Quality Control

Our Hypophyllanthin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the stringent requirements for research and reference standards. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.