Description

3,5-Bis[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-Benzoic Acid Methyl Ester is a key protected intermediate in advanced organic synthesis, valued for its role in constructing complex molecular architectures. Its primary function is to serve as a versatile building block for pharmaceuticals and specialty chemicals, where precise functional group manipulation is critical. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-purity intermediates.

Application

• Pharmaceutical Intermediate: A crucial protected precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring specific phenolic or benzoic acid derivative motifs.
• Organic Synthesis Building Block: Used in multi-step synthesis for constructing complex molecules in medicinal chemistry and material science research.
• Agrochemical Research: Serves as an intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks.
• Polymer Chemistry: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploratory chemistry in laboratory settings.

Basic Information

Product Name	3,5-Bis[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-Benzoic Acid Methyl Ester
CAS No.	33617-41-3
Molecular Formula	C19H26O6
Molecular Weight	350.41 g/mol
Synonyms	Methyl 3,5-bis[(tetrahydro-2H-pyran-2-yl)oxy]benzoate; 3,5-Bis(2-tetrahydropyranyloxy)benzoic Acid Methyl Ester; Benzoic acid, 3,5-bis[(tetrahydro-2H-pyran-2-yl)oxy]-, methyl ester; Methyl 3,5-di-O-(tetrahydro-2H-pyran-2-yl)benzoate; 3,5-Di-O-THP-benzoic Acid Methyl Ester; 3,5-Bis(THP-Oxy) Methyl Benzoate; THP-protected Methyl 3,5-Dihydroxybenzoate
EINECS	Contact for details

Quality Control

Our production of 3,5-Bis[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-Benzoic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.