Description

Trimethylsilyl(Trimethylsiloxy)Acetate is a specialized organosilicon compound that serves as a versatile silylating agent and synthetic intermediate. Its bifunctional structure, featuring both a silyl ester and a silyl ether group, makes it a valuable reagent for introducing protective groups and modifying surface properties in advanced chemical synthesis. This product is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and advanced materials sectors seeking to enhance process efficiency and product performance.

Application

• Pharmaceutical Intermediate: Used as a key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for protecting hydroxyl and carboxyl groups during complex multi-step reactions.
• Agrochemical Synthesis: Employed in the production of advanced pesticides and herbicides, where its silylating properties aid in creating stable, bio-active molecules.
• Surface Modification Agent: Applied to modify the surface properties of silica, glass, and other inorganic materials to impart hydrophobicity or improve compatibility with organic matrices.
• Polymer & Resin Chemistry: Acts as a cross-linking agent or modifier in silicone-based polymers and specialty resins to tailor mechanical and thermal properties.
• Analytical Derivatization: Utilized in gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) to derivative polar compounds (e.g., acids, alcohols) for improved volatility and detection.
• Electronics & Semiconductor Precursor: Serves as a precursor in chemical vapor deposition (CVD) processes for depositing silicon-containing thin films.

Basic Information

Product Name	Trimethylsilyl(Trimethylsiloxy)Acetate
CAS No.	33581-77-0
Molecular Formula	C8H20O3Si2
Molecular Weight	220.41 g/mol
Synonyms	Acetic acid, 2-(trimethylsiloxy)-, trimethylsilyl ester; Trimethylsilyl 2-(trimethylsiloxy)acetate; (Trimethylsiloxy)acetic acid trimethylsilyl ester; TMS-TMSO-Acetate; Bis(trimethylsilyl) glycolate; 2-(Trimethylsiloxy)acetic acid trimethylsilyl ester; Glycolic acid bis(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our Trimethylsilyl(Trimethylsiloxy)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.