Description

Methyl 2-Ethynylbenzoate is a specialized organic ester compound featuring a reactive ethynyl (acetylene) group on the aromatic ring. This unique structure makes it a valuable high-purity building block and key synthetic intermediate in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring alkyne functionalization for click chemistry or further derivatization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the ethynylbenzoate moiety is incorporated into the final active compound.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced organic materials with tailored properties.
• Organic Synthesis Building Block: Employed in Sonogashira coupling and other palladium-catalyzed reactions to introduce acetylene-substituted aromatic systems into target molecules.
• Ligand and Catalyst Development: Utilized for constructing complex organic ligands used in homogeneous catalysis and coordination chemistry.
• Fine Chemical Production: Functions as an intermediate in the multi-step synthesis of dyes, flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Methyl 2-Ethynylbenzoate
CAS No.	33577-99-0
Molecular Formula	C10H8O2
Molecular Weight	160.17 g/mol
Synonyms	2-Ethynylbenzoic acid methyl ester; Methyl o-ethynylbenzoate; Benzoic acid, 2-ethynyl-, methyl ester; Methyl 2-ethynylbenzoate; 2-(Ethynyl)benzoic acid methyl ester; o-(Ethynyl)benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Ethynylbenzoate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. The compound may be sensitive to prolonged exposure to air and moisture; consider storage under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.