Description

10,17β-Bis(Acetyloxy)-3β-Fluoroestr-5-En-7-One is a high-purity, fluorinated steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for creating novel therapeutic agents, particularly in the fields of endocrinology and oncology. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex steroid-based molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel fluorinated steroid drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in academic and industrial research to study steroid receptor interactions, enzyme inhibition, and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Development: Employed in the discovery and early-stage development of new chemical entities (NCEs) targeting hormone-related conditions.
• Process Chemistry: Utilized for scaling up synthetic routes and optimizing production processes for steroid-based therapeutics.

Basic Information

Product Name	10,17β-Bis(Acetyloxy)-3β-Fluoroestr-5-En-7-One
CAS No.	33547-20-5
Molecular Formula	C24H31FO5
Molecular Weight	418.50 g/mol
Synonyms	3β-Fluoro-10β,17β-diacetoxyestr-5-en-7-one; 3β-Fluoro-10β,17β-dihydroxyestr-5-en-7-one diacetate; 10β,17β-Diacetoxy-3β-fluoroestr-5-en-7-one; 3-Fluoro-10,17-diacetoxyestr-5-en-7-one; Estr-5-ene-7-one, 10,17-bis(acetyloxy)-3-fluoro-, (3β,10β,17β)-; Fluoroestrone diacetate derivative
EINECS	Contact for details

Quality Control

Our 10,17β-Bis(Acetyloxy)-3β-Fluoroestr-5-En-7-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.