Description

Ethyl 5-(4-Chlorobenzoyl)-3-(Ethoxycarbonyl)-1,4-Dimethyl-1H-Pyrrole-2-Acetate is a high-purity, multi-functional pyrrole derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its complex molecular architecture, featuring both chlorobenzoyl and ethoxycarbonyl groups, makes it a versatile building block for constructing sophisticated heterocyclic compounds. This product is essential for research and development laboratories and production facilities focused on pharmaceuticals, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation pesticides, herbicides, and fungicides due to its bioactive pyrrole core.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in display and lighting technologies.
• Coordination Chemistry & Ligand Design: The pyrrole structure can be utilized to create complexing agents or ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and heterocycle formation.
• Specialty Chemical Production: Intermediate for dyes, pigments, and other performance chemicals requiring a specific, functionalized heterocyclic backbone.

Basic Information

Item	Details
Product Name	Ethyl 5-(4-Chlorobenzoyl)-3-(Ethoxycarbonyl)-1,4-Dimethyl-1H-Pyrrole-2-Acetate
CAS No.	33369-27-6
Molecular Formula	C20H22ClNO5
Molecular Weight	391.85 g/mol
Synonyms	5-(4-Chlorobenzoyl)-3-(ethoxycarbonyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid ethyl ester; Ethyl 5-(p-chlorobenzoyl)-3-(ethoxycarbonyl)-1,4-dimethyl-1H-pyrrole-2-acetate; 1,4-Dimethyl-5-(4-chlorobenzoyl)-3-(ethoxycarbonyl)-1H-pyrrole-2-acetic acid ethyl ester; 1H-Pyrrole-2-acetic acid, 5-(4-chlorobenzoyl)-3-(ethoxycarbonyl)-1,4-dimethyl-, ethyl ester; CAS 33369-27-6; Pyrrole-2-acetate derivative intermediate
EINECS	Contact for details

Quality Control

Our Ethyl 5-(4-Chlorobenzoyl)-3-(Ethoxycarbonyl)-1,4-Dimethyl-1H-Pyrrole-2-Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers must be kept sealed under an inert atmosphere such as nitrogen or argon after opening to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.