Description

Ethyl Dl-Threoninate Hydrochloride (CAS NO 33368-36-4) is a protected amino acid derivative of significant value in synthetic organic chemistry. This compound serves as a crucial chiral building block and intermediate for the preparation of more complex peptides, pharmaceuticals, and fine chemicals. It is primarily utilized by research institutions, pharmaceutical development labs, and specialty chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), peptidomimetics, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the multi-step synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protected threonine derivative in solid-phase and solution-phase peptide synthesis to construct specific peptide sequences.
• Biochemical Research: Serves as a standard or reagent in metabolic pathway studies and enzymatic research involving amino acids.
• Fine Chemical Synthesis: A versatile intermediate for creating custom-designed molecules in agrochemical and material science research.
• Asymmetric Synthesis: Employed in catalytic asymmetric reactions to introduce chirality into target molecules.
• Protecting Group Strategy: The ethyl ester and hydrochloride salt forms provide stability during complex synthetic transformations.

Basic Information

Product Name	Ethyl Dl-Threoninate Hydrochloride
CAS No.	33368-36-4
Molecular Formula	C6H14ClNO3
Molecular Weight	183.63 g/mol
Synonyms	DL-Threonine ethyl ester hydrochloride; Ethyl DL-threoninate HCl; (±)-Threonine ethyl ester hydrochloride; 2-Amino-3-hydroxybutyric acid ethyl ester hydrochloride; Ethyl 2-amino-3-hydroxybutanoate hydrochloride; Threonine ethyl ester hydrochloride (racemic); H-Thr-OEt·HCl; Ethyl threoninate hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl Dl-Threoninate Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent decomposition. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Racemic mixture (DL)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.