Description

2'-[(Trimethylsilyl)Oxy]Butyrophenone is a specialized organosilicon compound featuring a trimethylsilyl-protected phenolic hydroxyl group. This chemical serves as a valuable protected intermediate and synthetic building block in advanced organic synthesis, enabling precise control over reaction pathways. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the development of complex molecules, including active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: Key protected synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Serves as a crucial building block for constructing specialty organic compounds, including ligands and advanced materials.
• Research & Development: Used in academic and industrial R&D laboratories for method development and exploring new synthetic routes.
• Agrochemical Development: Potential intermediate in the synthesis of novel crop protection agents and herbicides.
• Material Science: Can be utilized in the preparation of silicon-containing polymers or surface-modifying agents.

Basic Information

Product Name	2'-[(Trimethylsilyl)Oxy]Butyrophenone
CAS No.	33342-90-4
Molecular Formula	C₁₃H₂₀O₂Si
Molecular Weight	236.39 g/mol
Synonyms	2'-(Trimethylsiloxy)butyrophenone; 1-[2-(Trimethylsilyloxy)phenyl]-1-butanone; Butyrophenone, 2'-(trimethylsilyloxy)-; 2-Trimethylsiloxybutyrophenone; 2'-Hydroxybutyrophenone trimethylsilyl ether; TMS-protected 2'-hydroxybutyrophenone; 2'-(TMS-O)Butyrophenone
EINECS	Contact for details

Quality Control

Our 2'-[(Trimethylsilyl)Oxy]Butyrophenone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.