Description

4'-[(Trimethylsilyl)Oxy]Propiophenone is a specialized organosilicon compound featuring a trimethylsilyl-protected phenolic hydroxyl group. This chemical serves as a crucial protected intermediate and synthetic building block in advanced organic synthesis, enabling precise chemical transformations. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Organic Synthesis Reagent: Used as a protected phenol derivative in multi-step synthesis, including Grignard reactions and nucleophilic substitutions.
• Chemical Research & Development: Essential for exploring new synthetic pathways and methodologies in academic and industrial R&D laboratories.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands and organometallic catalysts.
• Material Science: Potential monomer or modifier in the development of specialty polymers and silicon-containing materials.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and herbicides.

Basic Information

Product Name	4'-[(Trimethylsilyl)Oxy]Propiophenone
CAS No.	33342-89-1
Molecular Formula	C12H18O2Si
Molecular Weight	222.36 g/mol
Synonyms	1-[4-[(Trimethylsilyl)oxy]phenyl]-1-propanone; 4-(Trimethylsilyloxy)propiophenone; p-(Trimethylsilyloxy)propiophenone; Propiophenone, 4'-[(trimethylsilyl)oxy]-; 4'-Hydroxypropiophenone trimethylsilyl ether; TMS-protected 4'-hydroxypropiophenone; 4'-OTMS Propiophenone
EINECS	Contact for details

Quality Control

Our 4'-[(Trimethylsilyl)Oxy]Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for sensitive pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.