Description

3'-[(Trimethylsilyl)Oxy]Propiophenone is a specialized organosilicon building block used in advanced organic synthesis. This compound is valued for its role as a protected intermediate, enabling the controlled introduction of functional groups in complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the preparation of advanced intermediates for agrochemicals, flavors, and fragrances.
• Academic & Industrial Research: Serves as a versatile starting material in methodological development and novel compound library generation.
• Process Chemistry: Employed in scale-up and optimization studies for the development of robust and efficient synthetic routes.

Basic Information

Product Name	3'-[(Trimethylsilyl)Oxy]Propiophenone
CAS No.	33342-88-0
Molecular Formula	C12H18O2Si
Molecular Weight	222.36 g/mol
Synonyms	1-[3-[(Trimethylsilyl)oxy]phenyl]-1-propanone; 3-(Trimethylsilyloxy)propiophenone; 3'-Hydroxypropiophenone trimethylsilyl ether; Propiophenone, 3'-[(trimethylsilyl)oxy]-; m-(Trimethylsiloxy)propiophenone; 3-TMS-Oxypropiophenone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, assay, and impurity profiles are available upon request. We adhere to strict in-process controls to deliver material suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.