Description

[(20R)-5α-Pregnane-3α,17,20-Triyl]Tri(Oxy)]Tris(Trimethylsilane) CAS NO 33287-34-2 is a high-purity, synthetic steroid derivative, specifically a silyl ether-protected pregnane triol. This compound is a critical advanced pharmaceutical intermediate (API intermediate) and a valuable building block in organic synthesis. It is primarily used by pharmaceutical R&D and fine chemical synthesis teams for the development and production of steroid-based therapeutics and other complex organic molecules.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the production of steroid hormones and related active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in multi-step synthesis to introduce the protected pregnane backbone into more complex molecular architectures.
• Research & Development: Essential reference standard and starting material in medicinal chemistry for exploring new therapeutic agents.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for steroid derivatives in pilot plants and manufacturing.
• Biochemical Research: Used in studies investigating steroid metabolism, receptor binding, and enzymatic pathways.

Basic Information

Product Name	[(20R)-5α-Pregnane-3α,17,20-Triyl]Tri(Oxy)]Tris(Trimethylsilane)
CAS No.	33287-34-2
Molecular Formula	C32H64O3Si3
Molecular Weight	581.1 g/mol
Synonyms	(20R)-5α-Pregnane-3α,17,20-triol tris(trimethylsilyl) ether; 5α-Pregnane-3α,17,20-triol, tris-O-(trimethylsilyl)-, (20R)-; Pregnane-3α,17,20-triol tris-TMS ether; Tris(trimethylsilyl) ether of (20R)-5α-pregnane-3α,17,20-triol; Steroid TMS derivative; TMS-protected pregnane triol
EINECS	Contact for details

Quality Control

Our [(20R)-5α-Pregnane-3α,17,20-Triyl]Tri(Oxy)]Tris(Trimethylsilane) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.