Description

3β,25-Bis(Trimethylsiloxy)Cholest-5-Ene is a high-purity, organosilicon-modified sterol derivative, serving as a critical advanced intermediate in sophisticated organic synthesis. Its value lies in the strategic protection of hydroxyl groups, enabling precise chemical transformations in sensitive molecular frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-based therapeutics and hormone analogs.
• Advanced Organic Synthesis: Used as a protected sterol precursor in multi-step synthesis for complex natural products and fine chemicals.
• Research & Development: Critical reagent in medicinal chemistry for structure-activity relationship (SAR) studies and new drug candidate exploration.
• Agrochemical Synthesis: Intermediate in the development of new generation plant growth regulators and bioactive agrochemicals.
• Material Science: Potential precursor for creating functionalized sterol-based polymers or liquid crystal materials.
• Bioconjugation Chemistry: Used to introduce hydrophobic, silyl-protected anchors into biomolecules for various applications.

Basic Information

Product Name	3β,25-Bis(Trimethylsiloxy)Cholest-5-Ene
CAS No.	33287-27-3
Molecular Formula	C33H62O2Si2
Molecular Weight	547.0 g/mol
Synonyms	Cholest-5-ene-3β,25-diol, bis(trimethylsilyl) ether; 3β,25-Bis-O-(trimethylsilyl)cholest-5-ene; 25-(Trimethylsiloxy)-3β-(trimethylsiloxy)cholest-5-ene; 3β,25-Bis(trimethylsilyloxy)cholest-5-ene; 3β,25-Di-O-trimethylsilylcholest-5-ene; Silylated Cholestenediol Derivative; TMS-protected cholestenediol
EINECS	Contact for details

Quality Control

Our 3β,25-Bis(Trimethylsiloxy)Cholest-5-Ene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.