Description

Ethanone, 2,2,2-Trifluoro-1-(3-Pyridinyl)- (9Ci) is a high-purity trifluoromethyl ketone derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a pyridine ring and a reactive trifluoroacetyl group, makes it an invaluable intermediate for creating complex molecules with tailored properties. This compound is essential for R&D and production in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and manufacture of advanced pesticides and herbicides, leveraging the stability and bioactivity of the trifluoromethyl group.
• Ligand and Catalyst Precursor: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials for electronic and optical applications.
• Fluorine Chemistry Building Block: A versatile reagent for introducing the trifluoroacetyl moiety into complex molecular architectures in academic and industrial R&D.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(3-Pyridinyl)- (9Ci)
CAS No.	33284-21-8
Molecular Formula	C8H4F3NO
Molecular Weight	187.12 g/mol
Synonyms	3-(Trifluoroacetyl)pyridine; 1-(3-Pyridinyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(pyridin-3-yl)ethanone; 3-Pyridyl trifluoromethyl ketone; α,α,α-Trifluoro-3-pyridyl methyl ketone; 3-Trifluoroacetylpyridine; 3-Pyridinyl trifluoromethyl ketone; TFAP
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(3-Pyridinyl)- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, GC, and NMR, to verify identity and purity. Certificates of Analysis (COA) are available for every batch and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging, or stored in darkness.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.