Description

3β,11β-Bis(Trimethylsiloxy)-5α-Androstane is a key steroidal intermediate, specifically a silyl-protected derivative of 5α-androstane. This compound is crucial for providing a stable, protected framework for the controlled synthesis of more complex steroid-based molecules. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and metabolic research.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of advanced steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for exploring new synthetic pathways and creating novel steroid analogs for biological evaluation.
• Hormone Analog Synthesis: Serves as a precursor in the development of modified androstane derivatives with potential therapeutic applications.
• Fine Chemical Production: Employed in the manufacture of high-value, specialty chemicals for the life sciences sector.
• Reference Standard: Can be utilized as a chromatographic or spectroscopic standard for quality control in related synthetic processes.

Basic Information

Product Name	3β,11β-Bis(Trimethylsiloxy)-5α-Androstane
CAS No.	33283-00-0
Molecular Formula	C25H46O2Si2
Molecular Weight	434.81 g/mol
Synonyms	5α-Androstane-3β,11β-diol bis(trimethylsilyl) ether; 3β,11β-Bis-O-(trimethylsilyl)-5α-androstane; 5α-Androstane-3β,11β-diyl bis(oxy)bis(trimethylsilane); Androstane-3β,11β-diol, bis(trimethylsilyl) ether; 3β,11β-Bis(trimethylsiloxy)androstane; 3β,11β-Di(trimethylsiloxy)-5α-androstane
EINECS	Contact for details

Quality Control

Our 3β,11β-Bis(Trimethylsiloxy)-5α-Androstane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can compromise product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.