Description

5-(2,4-Dimethoxyphenyl)-3-Isoxazolecarboxylic Acid Ethyl Ester is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a versatile building block in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, heterocyclic compounds, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing the isoxazole heterocycle, which is a privileged scaffold in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the dimethoxyphenyl and isoxazole motifs can contribute to biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a potential building block for electron-transport materials or emissive layer components in OLED research due to its conjugated structure.
• Ligand and Catalyst Development: The ester and heterocyclic functionalities make it a candidate for modifying ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: Employed in universities and corporate labs for methodological studies in organic synthesis, such as cross-coupling reactions and heterocycle formation.
• Fine Chemical Production: Integrated into multi-step synthetic routes for producing high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Item	Details
Product Name	5-(2,4-Dimethoxyphenyl)-3-Isoxazolecarboxylic Acid Ethyl Ester
CAS No.	33277-16-6
Molecular Formula	C14H15NO5
Molecular Weight	277.27 g/mol
Synonyms	Ethyl 5-(2,4-dimethoxyphenyl)isoxazole-3-carboxylate; 3-Isoxazolecarboxylic acid, 5-(2,4-dimethoxyphenyl)-, ethyl ester; Ethyl 5-(2,4-dimethoxyphenyl)-1,2-oxazole-3-carboxylate; 5-(2,4-Dimethoxyphenyl)isoxazole-3-carboxylic acid ethyl ester; NSC 339586; AI3-23900; 33277-16-6
EINECS	Contact for details

Quality Control

Our 5-(2,4-Dimethoxyphenyl)-3-Isoxazolecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.