Description

tert-Butyl 2-(4-Bromophenyl)Acetate is a high-purity organic building block and synthetic intermediate of significant importance in advanced chemical synthesis. Its core value lies in providing a protected carboxylic acid functionality and a versatile aryl bromide handle, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for complex organic transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biphenyl or substituted phenylacetic acid motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and other crop protection agents where the 4-bromophenyl group is a critical structural element.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in cross-coupling reactions like Suzuki-Miyaura couplings.
• Material Science Research: Employed in the creation of novel organic frameworks, liquid crystals, and polymers with tailored electronic or optical properties.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to the reactivity of the bromine atom for further functionalization.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories engaged in novel synthetic route development.

Basic Information

Product Name	tert-Butyl 2-(4-Bromophenyl)Acetate
CAS No.	33155-58-7
Molecular Formula	C12H15BrO2
Molecular Weight	271.15 g/mol
Synonyms	4-Bromophenylacetic Acid tert-Butyl Ester; 2-(4-Bromophenyl)acetic Acid 1,1-Dimethylethyl Ester; tert-Butyl (4-Bromophenyl)acetate; (4-Bromophenyl)acetic Acid tert-Butyl Ester; 1,1-Dimethylethyl 2-(4-Bromophenyl)acetate; t-Butyl 4-Bromophenylacetate; TBPA; 33155-58-7
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(4-Bromophenyl)Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.