Description

2-Isocyano-3-(Methylthio)-Propionic Acid Methyl Ester is a versatile and reactive organic building block containing both isocyano and methylthio functional groups. This compound is valued for its role as a key intermediate in the synthesis of complex heterocyclic structures and functionalized amino acid derivatives. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of heterocyclic compounds with potential biological activity, such as thiazoles and imidazoles.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactive isocyano group.
• Peptidomimetics & Amino Acid Derivatives: Serves as a building block for creating modified peptides and non-natural amino acids for drug discovery.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme activity and biological pathways.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory organic synthesis.

Basic Information

Product Name	2-Isocyano-3-(Methylthio)-Propionic Acid Methyl Ester
CAS No.	33115-77-4
Molecular Formula	C6H9NO2S
Molecular Weight	159.20 g/mol
Synonyms	Methyl 2-Isocyano-3-(methylthio)propanoate; Methyl 3-(Methylthio)-2-isocyanopropionate; 2-Isocyano-3-methylsulfanyl-propionic acid methyl ester; 3-(Methylthio)-2-isocyanopropionic Acid Methyl Ester; NSC 334058; Methyl (methylthio)cyanoacetate (related structure); Isocyanoacetic acid 3-(methylthio) methyl ester
EINECS	Contact for details

Quality Control

Our 2-Isocyano-3-(Methylthio)-Propionic Acid Methyl Ester is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure consistency and reliability for your synthetic applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.