Description

Methyl 2-Isocyanopropionate, 96 CAS NO 33115-74-1 is a versatile organic building block featuring both an isocyanate and an ester functional group. This bifunctional nature makes it a critical intermediate for synthesizing a wide range of complex molecules, including pharmaceuticals, agrochemicals, and specialty polymers. It is essential for research and development chemists and process engineers in fine chemical and active pharmaceutical ingredient (API) manufacturing who require high-purity, reactive intermediates for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing urea, carbamate, or heterocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its reactive isocyanate group enables the formation of bioactive carbamate linkages.
• Polymer & Resin Modification: Serves as a cross-linking agent or chain extender in polyurethane and specialty polymer systems to modify mechanical and thermal properties.
• Peptide Mimetics & Bioconjugation: Employed in medicinal chemistry for creating peptide analogs and for bioconjugation strategies, attaching molecules to proteins or other biomolecules.
• Organic Synthesis Reagent: A valuable reagent in multi-step organic synthesis for introducing the isocyanate functionality under mild conditions, facilitating the construction of complex organic frameworks.

Basic Information

Item	Detail
Product Name	Methyl 2-Isocyanopropionate, 96
CAS No.	33115-74-1
Molecular Formula	C5H7NO3
Molecular Weight	129.11 g/mol
Synonyms	2-Isocyanopropionic Acid Methyl Ester; Methyl 2-Isocyanopropanoate; Methyl α-Isocyanopropionate; Methyl DL-2-Isocyanopropionate; 2-Isocyanato-2-methylpropanoic Acid Methyl Ester; Methyl 2-Isocyanato-2-methylpropanoate; Propanoic acid, 2-isocyanato-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Isocyanopropionate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including assay by GC or HPLC and impurity profiling, to ensure it meets the specified 96% purity grade and consistent performance. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.