Description

Spiro[Indene-1,4'-Piperidine] CAS NO 33042-66-9 is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic molecular architecture. This compound is of significant value in modern organic synthesis, serving as a critical building block for constructing complex molecules with potential biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in the construction of complex spirocyclic and heterocyclic compounds due to its rigid, three-dimensional structure.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents with novel modes of action.
• Material Science: Explored as a monomer or additive for creating specialty polymers with unique thermal or mechanical properties.

Basic Information

Product Name	Spiro[Indene-1,4'-Piperidine]
CAS No.	33042-66-9
Molecular Formula	C13H15N
Molecular Weight	185.27 g/mol
Synonyms	Spiro[indene-1,4'-piperidine]; 1'H-Spiro[indene-1,4'-piperidine]; 1,2,3,9b-Tetrahydrospiro[indene-1,4'-piperidine]; Spiro[indan-1,4'-piperidine]; 1,2,3,9b-Tetrahydro-1H-spiro[indene-1,4'-piperidine]; 33042-66-9; Spiro(1H-indene-1,4'-piperidine); Spiro[indene-1,4'-piperidine] (base)
EINECS	Contact for details

Quality Control

Our Spiro[Indene-1,4'-Piperidine] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.