Description

3-(2-Adamantyl)-1-(2-Fluoroethyl)-1-Nitrosourea is a specialized nitrosourea derivative, a class of compounds historically significant in medicinal chemistry research for their alkylating properties. This compound is valued for its unique molecular architecture, combining an adamantyl group for lipophilicity and metabolic stability with a fluoroethyl moiety, which can influence its biological activity and distribution. It is primarily utilized by research institutions and pharmaceutical development laboratories engaged in the synthesis of novel therapeutic agents, particularly in the exploration of oncology and central nervous system (CNS) drug candidates.

Application

• Pharmaceutical Research & Development: Serves as a key synthetic intermediate or a lead compound in the discovery of new anticancer agents, leveraging the nitrosourea group's DNA alkylation mechanism.
• Medicinal Chemistry Studies: Used to investigate structure-activity relationships (SAR) to optimize the potency, selectivity, and pharmacokinetic profile of alkylating agents.
• Biochemical Research: Employed in vitro studies to evaluate cytotoxic effects and mechanisms of action against various cancer cell lines.
• Preclinical Development: Acts as a candidate molecule for pharmacokinetic, metabolic stability, and toxicology studies in animal models.
• Academic Research: Utilized in university laboratories for teaching and advanced research in organic synthesis and cancer biology.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in related API synthesis.

Basic Information

Product Name	3-(2-Adamantyl)-1-(2-Fluoroethyl)-1-Nitrosourea
CAS No.	33024-41-8
Molecular Formula	C₁₃H₂₀FN₃O₂
Molecular Weight	269.32 g/mol
Synonyms	1-(2-Fluoroethyl)-3-(2-adamantyl)-1-nitrosourea; 2-Fluoroethyl 2-Adamantyl Nitrosourea; NSC 33024; Adamantyl Fluoroethyl Nitrosourea; AFNU; 1-Nitrosourea, 3-(2-adamantyl)-1-(2-fluoroethyl)-; 3-(2-Adamantyl)-1-(2-fluoroethyl)nitrosourea
EINECS	Contact for details

Quality Control

Our 3-(2-Adamantyl)-1-(2-Fluoroethyl)-1-Nitrosourea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.