Description

N'-[4-(Acetyloxy)Cyclohexyl]-n-(2-Fluoroethyl)-n-Nitrosourea is a specialized nitrosourea derivative, a class of compounds known for their alkylating properties and significant research interest in medicinal chemistry. This compound matters for its potential as a key synthetic intermediate or a biologically active scaffold in the development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on oncology research, targeted drug delivery systems, and advanced organic synthesis.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel alkylating agents for potential anti-cancer therapies.
• Medicinal Chemistry Studies: Used as a model compound to study structure-activity relationships (SAR) of nitrosourea derivatives and their biological mechanisms.
• Preclinical Drug Discovery: Investigated for its efficacy and pharmacokinetic properties in early-stage in vitro and in vivo studies.
• Bioconjugation & Prodrug Synthesis: The reactive functional groups enable its use in creating targeted prodrugs or conjugates for enhanced drug delivery.
• Organic Synthesis Building Block: Employed in advanced organic synthesis to introduce the nitrosourea moiety into more complex molecular architectures.
• Biochemical Tool Compound: Utilized in laboratory research to study DNA alkylation, apoptosis induction, and other cellular processes.

Basic Information

Product Name	N'-[4-(Acetyloxy)Cyclohexyl]-n-(2-Fluoroethyl)-n-Nitrosourea
CAS No.	33024-40-7
Molecular Formula	C11H18FN3O4
Molecular Weight	275.28 g/mol
Synonyms	1-(4-Acetoxycyclohexyl)-3-(2-fluoroethyl)-1-nitrosourea; 1-(trans-4-Acetoxycyclohexyl)-3-(2-fluoroethyl)-1-nitrosourea; NSC 85998; FCNU; Fluroethyl Cyclohexyl Nitrosourea; N-(2-Fluoroethyl)-N'-[(4-acetyloxy)cyclohexyl]-N-nitrosourea; 1-Nitroso-1-[4-(acetyloxy)cyclohexyl]-3-(2-fluoroethyl)urea
EINECS	Contact for details

Quality Control

Our N'-[4-(Acetyloxy)Cyclohexyl]-n-(2-Fluoroethyl)-n-Nitrosourea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.