Description

3-(3-tert-Butylcyclohexyl)-1-(2-Chloroethyl)-1-Nitrosourea is a specialized nitrosourea derivative with a complex molecular architecture, designed for advanced research and development applications. This compound is valued for its unique structural features, including the tert-butylcyclohexyl and chloroethyl moieties, which are of significant interest in synthetic organic chemistry and pharmaceutical discovery. It serves as a critical intermediate or reference standard for researchers in medicinal chemistry, process development, and fine chemical synthesis, particularly for investigating novel bioactive molecules.

Application

• Pharmaceutical Research & Development: Acts as a key synthetic intermediate or building block in the discovery and development of novel therapeutic agents, particularly in oncology and CNS drug research.
• Medicinal Chemistry Studies: Used as a reference standard or a model compound for structure-activity relationship (SAR) studies due to its nitrosourea functional group.
• Process Chemistry & Scale-Up: Serves as a critical intermediate in the multi-step synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental research in organic synthesis methodologies and reaction mechanism studies.
• Chemical Biology Probes: Potential use in the development of chemical probes to study biological pathways and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	3-(3-tert-Butylcyclohexyl)-1-(2-Chloroethyl)-1-Nitrosourea
CAS No.	33021-96-4
Molecular Formula	C₁₃H₂₄ClN₃O₂
Molecular Weight	289.80 g/mol
Synonyms	1-(2-Chloroethyl)-3-(3-tert-butylcyclohexyl)-1-nitrosourea; 3-(3-tert-Butylcyclohexyl)-1-(2-chloroethyl)-1-nitrosourea; 1-Nitrosourea, 1-(2-chloroethyl)-3-(3-(1,1-dimethylethyl)cyclohexyl)-; BCNU derivative (tert-butyl analog); N-(2-Chloroethyl)-N'-nitroso-N-(3-tert-butylcyclohexyl)urea; tert-Butyl CCNU analog; 33021-96-4
EINECS	Contact for details

Quality Control

Every batch of 3-(3-tert-Butylcyclohexyl)-1-(2-Chloroethyl)-1-Nitrosourea is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment to guarantee full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.