Description

Methyl 2,3-o-Isopropylidene-5-o-Benzyl-β-D-Ribofuranoside is a key protected ribofuranoside derivative, a crucial building block in synthetic organic chemistry. Its value lies in providing a versatile, selectively protected sugar scaffold for the controlled synthesis of complex nucleosides, nucleotides, and other bioactive molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries, where precise molecular construction is paramount for developing new active ingredients and probes.

Application

• Nucleoside/Nucleotide Synthesis: Serves as a critical precursor for the preparation of modified nucleosides, including antiviral and anticancer agents.
• Pharmaceutical Intermediates: Used in the multi-step synthesis of complex active pharmaceutical ingredients (APIs) requiring specific sugar moiety modifications.
• Oligonucleotide Chemistry: Acts as a protected monomer or starting material for the synthesis of oligonucleotides and their analogs for research and therapeutic applications.
• Glycochemistry & Glycobiology: Provides a versatile building block for constructing complex carbohydrate structures and glycoconjugates.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides that utilize nucleoside-like structures.
• Chemical Biology Probes: Used to create labeled or modified nucleoside probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	Methyl 2,3-o-Isopropylidene-5-o-Benzyl-β-D-Ribofuranoside
CAS No.	33019-63-5
Molecular Formula	C16H22O5
Molecular Weight	294.34 g/mol
Synonyms	Methyl 5-O-Benzyl-2,3-O-isopropylidene-β-D-ribofuranoside; 5-O-Benzyl-2,3-O-isopropylidene-β-D-ribofuranoside Methyl Glycoside; 1-O-Methyl-5-O-benzyl-2,3-O-isopropylidene-β-D-ribofuranose; Methyl 5-O-benzyl-2,3-O-(1-methylethylidene)-β-D-ribofuranoside; β-D-Ribofuranoside, methyl 5-O-benzyl-2,3-O-(1-methylethylidene)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity synthetic intermediates. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profiles are available upon request. We adhere to a cGMP-compliant quality management system to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture uptake. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (β-D isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.