Description

(R)-(-)-γ-Ethoxycarbonyl-γ-Butyrolactone CAS NO 33019-03-3 is a high-value chiral building block and intermediate in organic synthesis. This compound matters for its role as a key precursor in the synthesis of complex, optically active molecules, particularly in the pharmaceutical sector. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating enantiomerically pure active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of various active pharmaceutical ingredients (APIs), including GABA analogs and other neuroactive compounds.
• Asymmetric Synthesis: Used as a starting material or intermediate in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Agrochemical Research: Serves as a building block for developing novel, chiral pesticides and herbicides with improved efficacy and selectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is essential.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and catalysis research.

Basic Information

Product Name	(R)-(-)-γ-Ethoxycarbonyl-γ-Butyrolactone
CAS No.	33019-03-3
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	(R)-(-)-4-Carbethoxy-γ-butyrolactone; (R)-(-)-4-(Ethoxycarbonyl)-2-oxetanone; (R)-(-)-γ-Ethoxycarbonyl-γ-butyrolactone; (R)-(-)-4-Ethoxycarbonyl-2-oxetanone; (R)-(-)-Ethyl 4-oxotetrahydrofuran-3-carboxylate; (R)-(-)-3-Carbethoxy-γ-butyrolactone; (R)-(-)-γ-Carbethoxy-γ-butyrolactone; (R)-(-)-Ethyl 4-oxodihydrofuran-3-carboxylate
EINECS	Contact for details

Quality Control

Our (R)-(-)-γ-Ethoxycarbonyl-γ-Butyrolactone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]D20	-30° to -35° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.