Description

2'-Deoxyuridine 3'-Benzoate is a chemically modified nucleoside derivative, serving as a crucial protected intermediate in organic synthesis. This compound is valued for its role in the controlled synthesis of oligonucleotides and other nucleoside analogs, where selective protection of functional groups is required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing active pharmaceutical ingredients (APIs) and diagnostic probes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel antiviral and anticancer nucleoside drugs.
• Oligonucleotide Synthesis: Used as a protected monomer for the solid-phase or solution-phase synthesis of DNA and RNA analogs.
• Biochemical Research: Employed in studies of enzyme mechanisms, such as those involving thymidylate synthase, and in metabolic pathway investigations.
• Prodrug Development: Acts as a precursor molecule for designing prodrugs with enhanced bioavailability and targeted delivery.
• Fine Chemical Synthesis: Serves as a specialized intermediate for creating labeled compounds, molecular probes, and other high-value specialty chemicals.

Basic Information

Product Name	2'-Deoxyuridine 3'-Benzoate
CAS No.	33001-06-8
Molecular Formula	C16H16N2O6
Molecular Weight	332.31 g/mol
Synonyms	2'-Deoxyuridine 3'-monobenzoate; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-2,4(1H,3H)-pyrimidinedione 3'-benzoate; Uridine, 2'-deoxy-, 3'-benzoate; 3'-O-Benzoyl-2'-deoxyuridine; 2'-dUrd-3'-Bz; Deoxyuridine 3'-benzoate
EINECS	Contact for details

Quality Control

Our 2'-Deoxyuridine 3'-Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.