Description

Ethyl 3-Methylthiophene-2-Glyoxylate is a high-purity organic ester building block, specifically an α-ketoester derivative of a substituted thiophene. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, enabling the construction of complex heterocyclic scaffolds. It is primarily sought by research and development chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of thiophene-containing drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate the thiophene moiety for enhanced biological activity.
• Material Science Research: Serves as a precursor for the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to the electron-rich thiophene core.
• Chemical Synthesis: Utilized in organic methodology development, particularly in reactions like the Paal-Knorr synthesis, cyclocondensations, and as a substrate for asymmetric transformations.
• Fine Chemical Production: Intermediate in the custom synthesis of specialty chemicals, dyes, and complex fragrance molecules.

Basic Information

Product Name	Ethyl 3-Methylthiophene-2-Glyoxylate
CAS No.	32977-83-6
Molecular Formula	C9H10O3S
Molecular Weight	198.24 g/mol
Synonyms	Ethyl 3-methyl-2-thiopheneglyoxylate; Ethyl (3-methyl-2-thienyl)oxoacetate; 2-Thiopheneglyoxylic acid, 3-methyl-, ethyl ester; 3-Methylthiophene-2-glyoxylic acid ethyl ester; Ethyl 3-methylthiophene-2-glyoxylate; Oxo(3-methyl-2-thienyl)acetic acid ethyl ester; Glyoxylic acid, (3-methyl-2-thienyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Methylthiophene-2-Glyoxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.