Description

7-Methyl-n-(Trimethylsilyl)-6-[(Trimethylsilyl)Oxy]-7H-Purin-2-Amine CAS NO 32958-86-4 is a high-purity, silyl-protected purine derivative, a crucial building block in advanced organic synthesis. Its primary value lies in its role as a key protected intermediate for the development of nucleoside analogs and other biologically active compounds. This product is essential for research and development teams in the pharmaceutical, agrochemical, and fine chemical industries, particularly those focused on antiviral and anticancer drug discovery.

Application

• Pharmaceutical Intermediate: A critical protected synthon for the synthesis of novel nucleoside and nucleotide analogs with potential therapeutic applications.
• Antiviral Drug Research: Used in the R&D of purine-based antiviral agents targeting viral polymerases and replication mechanisms.
• Anticancer Agent Development: Serves as a building block for creating purine derivatives that act as kinase inhibitors or modulate cellular signaling pathways.
• Agrochemical Synthesis: Employed in the development of new plant growth regulators or pesticides based on modified nucleobase structures.
• Bioconjugation & Probe Synthesis: The silyl-protected functional groups allow for selective deprotection and further modification, useful in creating labeled probes for biochemical studies.
• Fine Chemical Manufacturing: Used in custom synthesis and contract manufacturing of complex, high-value specialty chemicals.

Basic Information

Item	Detail
Product Name	7-Methyl-n-(Trimethylsilyl)-6-[(Trimethylsilyl)Oxy]-7H-Purin-2-Amine
CAS No.	32958-86-4
Molecular Formula	C12H23N5OSi2
Molecular Weight	309.51 g/mol
Synonyms	2-Amino-7-methyl-6-[(trimethylsilyl)oxy]-N-(trimethylsilyl)-7H-purine; 2-Amino-7-methyl-6-(trimethylsiloxy)-N-(trimethylsilyl)-7H-purine; 7-Methyl-2-amino-6-(trimethylsiloxy)-N-(trimethylsilyl)purine; 7-Methyl-6-O-(trimethylsilyl)-N-(trimethylsilyl)guanine; Silylated 7-Methylguanine Derivative; TMS-protected 7-Methylguanine; NSC 339586; CAS 32958-86-4
EINECS	Contact for details

Quality Control

Our 7-Methyl-n-(Trimethylsilyl)-6-[(Trimethylsilyl)Oxy]-7H-Purin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.