Description

1,4-Dimethyl 2-Chloro-5-Nitrobenzene-1,4-Dicarboxylate is a high-purity, multi-functional aromatic ester derivative, serving as a critical advanced intermediate in organic synthesis. Its value lies in its precise molecular architecture, which provides reactive sites for constructing complex molecules with high selectivity and yield. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is utilized to synthesize active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of compounds with nitro-aromatic or chlorinated benzene cores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging its nitro and chloro substituents for biological activity.
• Organic Synthesis Research: Serves as a versatile precursor for palladium-catalyzed cross-coupling reactions, nucleophilic aromatic substitution, and reduction reactions in academic and industrial R&D settings.
• Dye and Pigment Intermediate: Employed in the synthesis of complex organic dyes and pigments, where the nitro group can be reduced to an amine for further diazotization and coupling.
• Material Science Precursor: Potential use in the development of specialty polymers and liquid crystals, where its ester groups and aromatic structure contribute to desired material properties.

Basic Information

Item	Details
Product Name	1,4-Dimethyl 2-Chloro-5-Nitrobenzene-1,4-Dicarboxylate
CAS No.	32888-86-1
Molecular Formula	C10H8ClNO6
Molecular Weight	273.63 g/mol
Synonyms	Dimethyl 2-Chloro-5-nitroterephthalate; 2-Chloro-5-nitroterephthalic Acid Dimethyl Ester; 1,4-Benzenedicarboxylic acid, 2-chloro-5-nitro-, 1,4-dimethyl ester; Methyl 2-chloro-5-nitroterephthalate; Terephthalic acid, 2-chloro-5-nitro-, dimethyl ester
EINECS	Contact for details

Quality Control

Our production of 1,4-Dimethyl 2-Chloro-5-Nitrobenzene-1,4-Dicarboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent composition. We provide detailed Certificates of Analysis (COA) for traceability and support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.