Description

5-Methyl-n-(Trimethylsilyl)-2-[(Trimethylsilyl)Oxy]-4-Pyrimidinamine is a specialized organosilicon-protected pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a protected amine and hydroxyl functionality, enabling precise, multi-step reactions in sensitive chemical environments. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, particularly in nucleoside and heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel antiviral and anticancer agents, particularly in modified nucleoside analogs.
• Agrochemical Synthesis: Used in constructing complex heterocyclic cores for next-generation herbicides and fungicides.
• Advanced Material Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and silicon-containing materials.
• Process Chemistry: Employed in multi-step synthesis where selective deprotection of silyl groups is required under mild conditions.
• Research & Development: A valuable tool for medicinal chemists in structure-activity relationship (SAR) studies and library synthesis.
• Custom Synthesis: Basis for producing tailored, high-value fine chemicals and custom intermediates for specific client projects.

Basic Information

Product Name	5-Methyl-n-(Trimethylsilyl)-2-[(Trimethylsilyl)Oxy]-4-Pyrimidinamine
CAS No.	32865-88-6
Molecular Formula	C11H23N3OSi2
Molecular Weight	269.49 g/mol
Synonyms	4-Amino-5-methyl-2-(trimethylsiloxy)pyrimidine, N-(trimethylsilyl)-; 5-Methyl-2-(trimethylsiloxy)-4-((trimethylsilyl)amino)pyrimidine; 4-Pyrimidinamine, 5-methyl-N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-; Bis(trimethylsilyl) protected 4-amino-5-methyl-2-hydroxypyrimidine; N,O-Bis(trimethylsilyl)-4-amino-5-methyl-2-hydroxypyrimidine
EINECS	Contact for details

Quality Control

Every batch of 5-Methyl-n-(Trimethylsilyl)-2-[(Trimethylsilyl)Oxy]-4-Pyrimidinamine undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for advanced synthetic applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.