Description

6-Methyl-9-(Trimethylsilyl)-9H-Purine is a high-value, organosilicon-modified purine derivative. This compound is a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis, prized for its role in modifying nucleoside chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of modified nucleosides and nucleotides with potential antiviral or anticancer activity.
• Organic Synthesis Reagent: Used as a silyl-protected purine derivative in complex multi-step syntheses, particularly in medicinal chemistry.
• Research & Development: Essential for academic and industrial R&D focused on nucleic acid chemistry, prodrug design, and chemical biology studies.
• Agrochemical Synthesis: Potential intermediate in the development of novel plant growth regulators or pesticides based on purine analogs.
• Material Science: Investigated for use in the creation of specialty polymers or functionalized surfaces where the purine moiety imparts specific properties.

Basic Information

Product Name	6-Methyl-9-(Trimethylsilyl)-9H-Purine
CAS No.	32865-79-5
Molecular Formula	C9H16N4Si
Molecular Weight	208.34 g/mol
Synonyms	9-(Trimethylsilyl)-6-methylpurine; 6-Methyl-9-(trimethylsilyl)purine; 6-Methyl-9-trimethylsilylpurine; 9H-Purine, 6-methyl-9-(trimethylsilyl)-; 6-Methyl-9-TMS-purine; N9-Trimethylsilyl-6-methylpurine; 6-Methylpurine, 9-trimethylsilyl derivative
EINECS	Contact for details

Quality Control

Our 6-Methyl-9-(Trimethylsilyl)-9H-Purine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP and ISO standards for research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.