Description

6-Dimethylamino-9-Trimethylsilyl-9H-Purine is a key silylated purine derivative, serving as a versatile building block in advanced organic synthesis. Its primary value lies in its role as a protected intermediate for the preparation of nucleoside analogs and other biologically active compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and life science industries, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside-based drug candidates, including potential antiviral and anticancer agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides that target specific biological pathways.
• Bioconjugation & Probe Synthesis: Acts as a reactive handle for labeling biomolecules or creating fluorescent probes for diagnostic applications.
• Material Science: Employed in the research of organic semiconductors and advanced polymeric materials requiring specific heterocyclic architectures.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	6-Dimethylamino-9-Trimethylsilyl-9H-Purine
CAS No.	32865-76-2
Molecular Formula	C12H21N5Si
Molecular Weight	263.42 g/mol
Synonyms	9-(Trimethylsilyl)-6-(dimethylamino)purine; 6-(Dimethylamino)-9-(trimethylsilyl)-9H-purine; 6-Dimethylaminopurine 9-trimethylsilyl ether; N,N-Dimethyl-9-(trimethylsilyl)purin-6-amine; 6-DMAP-TMS; TMS-6-DMAP; 6-Dimethylaminopurine TMS derivative
EINECS	Contact for details

Quality Control

Our 6-Dimethylamino-9-Trimethylsilyl-9H-Purine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and reactivity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.