Description

1-Acetoxy-2-Iodobenzene is a versatile aryl iodide derivative, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in its dual functional groups, enabling efficient cross-coupling reactions and serving as a protected precursor for ortho-substituted phenols. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring an ortho-iodophenol motif.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the iodine atom facilitates key carbon-carbon bond formations.
• Material Science Precursor: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as a reliable substrate in palladium-catalyzed reactions such as Suzuki, Stille, and Sonogashira couplings for biaryl synthesis.
• Organic Synthesis Reagent: Serves as a protected form of 2-iodophenol, allowing for selective functionalization in multi-step synthetic routes.
• Research & Development: A valuable tool for medicinal chemistry and process chemistry research in academic and industrial laboratories.

Basic Information

Product Name	1-Acetoxy-2-Iodobenzene
CAS No.	32865-61-5
Molecular Formula	C8H7IO2
Molecular Weight	262.05 g/mol
Synonyms	2-Iodophenyl acetate; o-Iodophenyl acetate; (2-Iodophenoxy)acetyl; Acetic acid 2-iodophenyl ester; 1-Acetoxy-2-iodobenzene; 2-Acetoxyiodobenzene; 2-Iodophenol acetate
EINECS	Contact for details

Quality Control

Our 1-Acetoxy-2-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.