Description

Methyl 4-Chloro-3-Oxo-Butanoate is a versatile chlorinated ketoester building block, essential for synthesizing complex organic molecules. Its reactive carbonyl and chloromethyl groups make it a key intermediate for constructing heterocycles and fine chemicals. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing β-keto ester or heterocyclic motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging its reactivity to form complex molecular structures.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and specialty chemicals requiring specific chlorinated ketone functionalities.
• Academic & Industrial Research: A valuable reagent in organic chemistry research for method development and exploring new synthetic pathways.
• Chemical Synthesis: Employed in Claisen condensation and alkylation reactions to form carbon-carbon bonds for more complex molecules.

Basic Information

Product Name	Methyl 4-Chloro-3-Oxo-Butanoate
CAS No.	32807-28-6
Molecular Formula	C5H7ClO3
Molecular Weight	150.56 g/mol
Synonyms	Methyl 4-chloroacetoacetate; 4-Chloro-3-oxobutanoic acid methyl ester; Methyl 4-chloro-3-oxobutyrate; Acetoacetic acid, 4-chloro-, methyl ester; Methyl γ-chloroacetoacetate; 3-Oxobutanoic acid, 4-chloro-, methyl ester; Methyl (4-chloro-3-oxobutanoate)
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloro-3-Oxo-Butanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging, or stored in darkness.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.