Description

Methyl 3-Butynoate is a versatile alkyne-containing ester that serves as a critical building block in advanced organic synthesis. Its terminal alkyne and ester functionalities make it a valuable precursor for constructing complex molecular architectures through reactions like Sonogashira coupling and Huisgen cycloaddition. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediates: A key synthon for constructing active pharmaceutical ingredients (APIs), particularly those containing heterocyclic or conjugated systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require alkyne motifs.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Click Chemistry: An ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create triazole linkages in bioconjugation and polymer chemistry.
• Organic Synthesis: Employed in Sonogashira coupling reactions to form carbon-carbon bonds for creating complex organic molecules in research and development.
• Liquid Crystal & OLED Materials: Used as a precursor in the synthesis of conjugated organic molecules for electronic and optoelectronic applications.

Basic Information

Product Name	Methyl 3-Butynoate
CAS No.	32804-66-3
Molecular Formula	C5H6O2
Molecular Weight	98.10 g/mol
Synonyms	3-Butynoic acid, methyl ester; Methyl but-3-ynoate; 3-Butynoic acid methyl ester; Methyl propiolate, 2-substituted; Methyl 3-butynoic acid ester; But-3-ynoic acid methyl ester; Propiolic acid, 2-substituted, methyl ester
EINECS	251-251-5

Quality Control

Our Methyl 3-Butynoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is between 2°C and 8°C (refrigerated) for long-term stability, although it can be stored at controlled room temperature (15-25°C) for shorter periods. Keep container tightly sealed when not in use to prevent moisture absorption and volatility loss.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.418 - 1.422
Density (20°C)	0.95 - 0.99 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.