Description

1-Bromo-1-(Difluoromethoxy)-2,2,2-Trifluoroethane is a specialized fluorinated organic compound that serves as a versatile building block in advanced chemical synthesis. Its unique molecular structure, featuring bromine and multiple fluorine atoms, makes it a valuable reagent for introducing fluorinated moieties into target molecules. This compound is primarily sought by research and development laboratories and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated structures for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key precursor in developing modern pesticides and herbicides, where fluorine atoms can enhance activity and environmental profile.
• Fluorinated Material Production: Acts as a monomer or modifier in the creation of specialty polymers, coatings, and liquid crystals with unique chemical resistance and surface properties.
• Organic Synthesis Reagent: Employed in research laboratories for nucleophilic substitution and other reactions to construct complex organic molecules.
• Refrigerant & Propellant Research: Investigated as a potential component in next-generation, environmentally friendly refrigerants and propellant blends due to its fluorinated structure.

Basic Information

Item	Detail
Product Name	1-Bromo-1-(Difluoromethoxy)-2,2,2-Trifluoroethane
CAS No.	32778-10-2
Molecular Formula	C3H2BrF5O
Molecular Weight	228.95 g/mol
Synonyms	2-Bromo-1,1,1-trifluoro-2-(difluoromethoxy)ethane; 1-Bromo-2,2,2-trifluoro-1-(difluoromethoxy)ethane; Bromodifluoromethoxytrifluoroethane; Halon 2402 substitute (research grade); Freon substitute intermediate; R-226ba (isomer designation); HCFC-226ba (historical/industrial context)
EINECS	Contact for details

Quality Control

Our production of 1-Bromo-1-(Difluoromethoxy)-2,2,2-Trifluoroethane adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous demands of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended storage temperature is between 2°C and 25°C. Keep away from strong bases and reactive metals.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.8 g/mL
Boiling Point	~60-70°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.