Description

Ethyl-(1-Isocyanocyclopropyl)-Carboxylate is a specialized organic building block featuring a reactive isocyanate group integrated into a strained cyclopropane ring. This compound matters for its unique structural motif, which enables the synthesis of novel heterocyclic compounds and complex molecular architectures with potential biological activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for lead optimization and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel nitrogen-containing heterocycles, such as β-lactams and fused ring systems, for drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the reactivity of the isocyanate and cyclopropane groups.
• Chemical Biology Probe Development: Serves as a versatile handle for bioconjugation and the synthesis of activity-based probes to study enzyme function.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for developing specialty polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Employed in methodological studies and the synthesis of complex natural product analogs in university and CRO laboratories.

Basic Information

Product Name	Ethyl-(1-Isocyanocyclopropyl)-Carboxylate
CAS No.	32755-45-6
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	Ethyl 1-Isocyanocyclopropanecarboxylate; 1-Isocyanocyclopropanecarboxylic Acid Ethyl Ester; Cyclopropanecarboxylic acid, 1-isocyanato-, ethyl ester; Ethyl 1-isocyanatocyclopropanecarboxylate; 32755-45-6; NSC 405124
EINECS	Contact for details

Quality Control

Our Ethyl-(1-Isocyanocyclopropyl)-Carboxylate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as indicated on the label. Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.