Description

(S)-2-Bromo-3,3-Dimethylbutyric Acid is a high-value chiral building block and intermediate in organic synthesis. This compound matters for its role in constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced materials. It is needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Ligand and Catalyst Development: Serves as a precursor for chiral phosphine ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Employed to introduce sterically hindered, bromine-functionalized side chains into peptide analogs for structure-activity relationship (SAR) studies.
• Material Science: Potential monomer or modifier for creating polymers with specific chiral or bulky pendant groups.

Basic Information

Product Name	(S)-2-Bromo-3,3-Dimethylbutyric Acid
CAS No.	32653-37-5
Molecular Formula	C6H11BrO2
Molecular Weight	195.06 g/mol
Synonyms	(S)-2-Bromo-3,3-dimethylbutanoic acid; (2S)-2-Bromo-3,3-dimethylbutyric acid; (S)-2-Bromo-3,3-dimethylbutanoate; (S)-α-Bromo-3,3-dimethylbutyric acid; (S)-2-Bromo-3,3-dimethylbutanoic Acid; Bromodimethylbutyric Acid (S-enantiomer); (S)-BDMBA; (S)-Bromo-3,3-dimethylbutanoic Acid
EINECS	Contact for details

Quality Control

Our (S)-2-Bromo-3,3-Dimethylbutyric Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Enantiomeric Excess (Chiral HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.