Description

(2S,3S)-2-Chloro-3-Methyl-n-Valeric Acid is a high-purity, chiral organic acid building block of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a critical intermediate for the development of enantiomerically pure pharmaceuticals and advanced agrochemicals. This compound is essential for research and production chemists in fine chemical, pharmaceutical, and agrochemical industries seeking to introduce specific chiral centers into complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other stereospecific drugs.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and pesticides where specific stereochemistry is required for optimal biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalytic reactions.
• Fine Chemical Research: A valuable building block in academic and industrial research for exploring new synthetic methodologies and creating novel chiral compounds.
• Peptidomimetics: Incorporated into the design and synthesis of peptide analogs and mimetics for drug discovery programs.

Basic Information

Product Name	(2S,3S)-2-Chloro-3-Methyl-n-Valeric Acid
CAS No.	32653-34-2
Molecular Formula	C6H11ClO2
Molecular Weight	150.60 g/mol
Synonyms	(2S,3S)-2-Chloro-3-methylpentanoic acid; (2S,3S)-2-Chloro-3-methylvaleric acid; L-threo-2-Chloro-3-methylvaleric acid; (2S,3S)-2-Chlor-3-methyl-valeriansäure; 2-Chloro-3-methyl-(2S,3S)-pentanoic acid; (2S,3S)-2-Chloro-3-methylpentanoate
EINECS	Contact for details

Quality Control

Our (2S,3S)-2-Chloro-3-Methyl-n-Valeric Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for stereochemical integrity and chemical purity. Certificates of Analysis (COA) detailing specific results for chiral excess, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from incompatible materials such as strong bases, oxidizing agents, and amines. The container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (2S,3S)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.