Description

(S)-2-Chloro-n-Butyric Acid CAS NO 32653-32-0 is a high-purity chiral building block essential for the synthesis of optically active compounds. Its value lies in the introduction of a stereogenic center and a reactive chloro handle for further functionalization, enabling the creation of complex molecules with high enantiomeric purity. This product is critically needed by research institutions and pharmaceutical companies developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure APIs, particularly for cardiovascular and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry enhances efficacy and reduces environmental impact.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as phosphines and oxazolines.
• Peptidomimetics Research: Employed to introduce non-natural amino acid analogs into peptide chains for drug discovery and biochemical studies.
• Flavor and Fragrance Industry: Acts as an intermediate for the synthesis of specific chiral esters and lactones that contribute to complex aroma profiles.
• Material Science: A monomer or co-monomer for creating specialized polymers with tailored optical or mechanical properties.

Basic Information

Product Name	(S)-2-Chloro-n-Butyric Acid
CAS No.	32653-32-0
Molecular Formula	C₄H₇ClO₂
Molecular Weight	122.55 g/mol
Synonyms	(S)-2-Chlorobutanoic Acid; (S)-2-Chlorobutyric Acid; (S)-α-Chlorobutyric Acid; L-2-Chlorobutyric Acid; (-)-2-Chlorobutyric Acid; (2S)-2-Chlorobutanoic Acid; (S)-2-Chloro-1-butanoic Acid; NSC 403697
EINECS	Contact for details

Quality Control

Our (S)-2-Chloro-n-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its nature as a strong acid/organic solvent, store separately from bases, oxidizing agents, and reactive metals.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.