Description

3-[4-Methoxy-3-(Trimethylsilyloxy)Phenyl]Propenoic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique silyl-protected phenolic structure. This compound is valued for its role as a versatile building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Utilized in coupling reactions, such as Heck or Suzuki reactions, to construct complex molecular frameworks.
• Medicinal Chemistry Research: Serves as a critical reagent in academic and industrial R&D for exploring new therapeutic compounds.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, including flavors, fragrances, and advanced materials.
• Protecting Group Chemistry: The trimethylsilyloxy group acts as a protective moiety for phenolic hydroxyl groups during synthetic sequences.

Basic Information

Product Name	3-[4-Methoxy-3-(Trimethylsilyloxy)Phenyl]Propenoic Acid Methyl Ester
CAS No.	32342-05-5
Molecular Formula	C14H20O4Si
Molecular Weight	280.40 g/mol
Synonyms	Methyl 3-[4-Methoxy-3-(trimethylsilyloxy)phenyl]propenoate; Methyl (E)-3-[4-Methoxy-3-(trimethylsilyloxy)phenyl]acrylate; 3-(4-Methoxy-3-((trimethylsilyl)oxy)phenyl)acrylic Acid Methyl Ester; (E)-Methyl 3-(4-methoxy-3-(trimethylsilyloxy)phenyl)acrylate; TMS-protected Methyl Ferulate Derivative; Methyl 3-(4-Methoxy-3-hydroxyphenyl)acrylate TMS Ether
EINECS	Contact for details

Quality Control

Our 3-[4-Methoxy-3-(Trimethylsilyloxy)Phenyl]Propenoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.