Description

2-Toluenesulfonyl Isocyanate is a versatile and highly reactive organic intermediate used for the introduction of the isocyanate functional group under mild conditions. This compound is particularly valued for its role as a key building block in the synthesis of sulfonylurea derivatives and other specialized chemicals. It is essential for research and development laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel compounds with specific biological or material properties.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of sulfonylurea drugs and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides and pesticides, particularly sulfonylurea-based crop protection agents.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for the modification of polymers to introduce specific functional groups.
• Peptide & Protein Research: Employed as a coupling agent or for modifying amino acid side chains in biochemical research.
• Organic Synthesis Reagent: A valuable tool for chemists to synthesize carbamates, ureas, and other isocyanate-derived compounds in a controlled manner.
• Material Science: Used in surface modification and the creation of advanced materials with tailored properties.

Basic Information

Product Name	2-Toluenesulfonyl Isocyanate
CAS No.	32324-19-9
Molecular Formula	C8H7NO3S
Molecular Weight	197.21 g/mol
Synonyms	o-Toluenesulfonyl Isocyanate; 2-Methylbenzenesulfonyl Isocyanate; Tosyl Isocyanate (o-isomer); TSI; 2-Tolylsulfonyl Isocyanate; Benzenesulfonyl Isocyanate, 2-methyl-; o-Tosyl Isocyanate; 2-Methylphenylsulfonyl Isocyanate
EINECS	Contact for details

Quality Control

Our 2-Toluenesulfonyl Isocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.