Description

7β-Tibolone CAS NO 32297-45-3 is a synthetic steroid hormone with a unique pharmacological profile. It is a critical active pharmaceutical ingredient (API) valued for its tissue-selective estrogenic, androgenic, and progestogenic activities. This compound is primarily required by pharmaceutical manufacturers for the development and production of hormone replacement therapies (HRT) and other specialized endocrine treatments.

Application

• Pharmaceutical API: Primary use as the active ingredient in hormone replacement therapy (HRT) medications for managing menopausal symptoms.
• Menopausal Symptom Management: Formulated to treat vasomotor symptoms (e.g., hot flashes), vaginal atrophy, and to prevent postmenopausal osteoporosis.
• Endocrine Research: Used as a reference standard and investigational compound in preclinical and clinical studies of steroid hormone action.
• Steroid Synthesis: Serves as a key intermediate or precursor in the synthesis of more complex steroid-based pharmaceuticals.
• Veterinary Pharmaceuticals: Potential application in veterinary medicine for hormonal regulation in animals.

Basic Information

Item	Details
Product Name	7β-Tibolone
CAS No.	32297-45-3
Molecular Formula	C21H28O2
Molecular Weight	312.45 g/mol
Synonyms	Tibolone; 7α,17α-17-Hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one; Livial®; Org OD-14; 7-Methylnorethynodrel; (7α,17α)-17-Hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one
EINECS	Contact for details

Quality Control

Our 7β-Tibolone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets high-grade pharmaceutical standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.