Description

2-Dehydro-3-Methoxy 7β-Tibolone is a high-purity synthetic steroid intermediate of significant commercial and research importance. Its primary value lies in its role as a key precursor in the synthesis of Tibolone, a medication used in hormone replacement therapy. This compound is essential for pharmaceutical manufacturers and advanced research institutions focused on developing and producing steroidal therapeutics. We supply this critical intermediate with a focus on consistent quality, reliable purity, and secure global logistics to support your production and development pipelines.

Application

• Pharmaceutical Active Ingredient (API) Synthesis: Primary use as a crucial intermediate in the multi-step synthesis of the steroid Tibolone.
• Hormone Replacement Therapy (HRT) Drug Development: Serves as a building block in R&D for novel steroidal compounds targeting menopausal symptom management.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.
• Process Chemistry Research: Employed in academic and industrial research to study steroidal transformation pathways and optimize synthetic routes.
• Bulk Pharmaceutical Manufacturing: Supplied to contract manufacturing organizations (CMOs) and large-scale API producers for commercial drug production.

Basic Information

Product Name	2-Dehydro-3-Methoxy 7β-Tibolone
CAS No.	32297-44-2
Molecular Formula	C21H28O2
Molecular Weight	312.45 g/mol
Synonyms	7β-Hydroxy-7α-methyl-19-nor-17α-pregn-5(10)-en-20-yn-3-one 3-Methyl Ether; Org OD-14 Intermediate; Tibolone Impurity; Tibolone Intermediate; 7α-Methyl-19-nor-17α-pregna-5(10)-en-20-yn-3-one, 7β-hydroxy-, 3-methyl ether; Livial Intermediate
EINECS	Contact for details

Quality Control

Every batch of 2-Dehydro-3-Methoxy 7β-Tibolone is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and compliance with your regulatory requirements. Our standard quality commitment includes identity confirmation by spectroscopic methods, purity determination by HPLC, and control of specific impurities. Certificates of Analysis (COA) detailing batch-specific results are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.