Description

[[(20R)-Pregn-5-Ene-3β,11β,17,20-Tetryl]Tetra(Oxy)]Tetrakis(Trimethylsilane) CAS NO 32221-73-1 is a high-purity, fully protected steroid derivative, specifically designed as a critical synthetic intermediate. Its value lies in enabling complex, multi-step organic synthesis with high selectivity and yield, particularly for the construction of advanced steroid-based molecules. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries working on novel therapeutic agents, including corticosteroids and other bioactive steroids.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex corticosteroid analogs and other steroidal active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in advanced organic synthesis for the preparation of novel steroid derivatives with potential biological activity.
• Research & Development: Serves as a crucial reagent in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for steroidal compounds under controlled conditions.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in steroid analysis.

Basic Information

Product Name	[[(20R)-Pregn-5-Ene-3β,11β,17,20-Tetryl]Tetra(Oxy)]Tetrakis(Trimethylsilane)
CAS No.	32221-73-1
Molecular Formula	C40H84O4Si4
Molecular Weight	741.5 g/mol
Synonyms	3β,11β,17,20-Tetrakis(trimethylsilyloxy)pregn-5-ene; Pregn-5-ene-3β,11β,17,20-tetrol, tetra(trimethylsilyl) ether; 3β,11β,17,20-Tetrakis-O-(trimethylsilyl)pregn-5-ene; TMS-protected pregnenetetrol; Pregn-5-ene-3,11,17,20-tetrayl tetra(trimethylsilyl) ether; (20R)-3β,11β,17,20-Tetrakis(trimethylsiloxy)pregn-5-ene
EINECS	Contact for details

Quality Control

Our [[(20R)-Pregn-5-Ene-3β,11β,17,20-Tetryl]Tetra(Oxy)]Tetrakis(Trimethylsilane) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can compromise the compound's stability and reactivity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.